Friday, December 14, 2012

No Chip in Arm, No Shot From Gun

Associated Press 04.14.04

The VeriChip technology is the latest attempt to create a so-called "smart gun" and could be marketed to law enforcement agencies within a year, according to the company.
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PALM BEACH, Florida -- A new computer chip promises to keep police guns from firing if they fall into the wrong hands.

The tiny chip would be implanted in a police officer's hand and would match up with a scanning device inside a handgun. If the officer and gun match, a digital signal unlocks the trigger so it can be fired. But if a child or criminal would get hold of the gun, it would be useless.

The technology is the latest attempt to create a so-called "smart gun" and could be marketed to law enforcement agencies within a year, according to Verichip, which has created the microchip.

Verichip president Keith Bolton said the technology could also improve safety for the military and individual gun owners.

"If you let your mind wander to other potential uses, you can imagine the lives that could be saved," he said.

Verichip, which has marketed similar microchips for security and medical purposes, announced Tuesday a partnership with gun maker FN Manufacturing to produce the smart weapons. The companies have developed a prototype and are working to refine its accuracy, Bolton said.

Similar developments are under way at other gun manufacturers and research firms. The New Jersey Institute of Technology and Australian gun maker Metal Storm Ltd. are working on a prototype smart gun that would recognize its owner's individual grip.

"We're at an interesting age where all sorts of science fiction is becoming real technology," said Donald Sebastian, NJIT vice president for research and development and director of the project.

The technology could also eventually have an even bigger impact on the illegal gun trade, Sebastian said.

The FBI estimated that 67 percent of the 16,204 murders in 2002 were committed with firearms.

"You have a long-term benefit of making it much more difficult for a handgun to have any value to anyone other than the original owner," Sebastian said.

But until the smart-gun technology is repeatedly proved to be reliable, some law enforcement authorities remain leery.

The scanning device could malfunction, the officer's hand with the computer chip could be smashed during a fight or an officer might need to use a partner's gun, West Palm Beach police training Sgt. William Sandman said.

"We have power outages, computers crash. Would you risk your life knowing all those things that could go wrong?" Sandman said.

Verichip's Bolton said those concerns already are being addressed. He said the guns can be designed to work for an officer, his partner and a supervisor. Departments could set routines where the scanning devices in guns could be checked before every shift.

The chip needs no battery or power source. It works much like those that have been implanted in pets over the past decade so they can be identified if they get lost. Verichip, a subsidiary of Applied Digital Solutions, developed a "more intelligent" version two years ago for humans and estimates that about 900 people worldwide have been implanted with them.

The chips can be used instead of security key cards at office buildings or to use global positioning satellites to keep track of a relative who might suffer from Alzheimer's. It can store medical information that emergency rooms could read or financial and identification information to prevent fraud.

The chip, about the size of a grain of rice, is inserted into an arm or hand with a syringe, much like a shot is given.

Bolton said the company has seen no medical complications and that the technology will only improve with time.

Once the technology is accepted, legislation could follow to encourage the use of smart guns. New Jersey already has passed legislation that will require smart-gun technology on all handguns sold -- three years after the state attorney general certifies that smart guns are available in the marketplace.

The National Rifle Association opposes the legislation because of potential problems with smart-gun technology, but gun safety advocates argue that the technology could encourage gun ownership with the new found sense of security.

"It seems that guns are the only product that haven't followed a path of development that leads to greater safety for the user. The only real change we've seen is to make them more lethal and smaller so they can be more easily concealed," said Rob Wilcox, a spokesman for the Brady Center to Prevent Gun Violence. "This is one of the steps that hasn't been taken, and we think this debate is one that needs to take place."

Thursday, December 13, 2012

Cancer More Diverse than Its Genetics

Tumor cells can exhibit different behaviors despite being genetically indistinguishable.
By Ruth Williams | December 13, 2012


One reason certain tumors can be hard to eliminate is that they contain a variety of different cells. This inherent heterogeneity was thought to be driven largely by the cells’ high mutation rates, but a report published in Science today (December 13) adds to growing evidence that non-genetic factors are also responsible.

“The take home message is, yes, it is important to know . . . what the genetic heterogeneity [of cancer] is, but heterogeneity among genetically-stable [cell lineages] is a factor that you also have to consider,” said Stephen Baylin, professor of oncology at The Johns Hopkins University School of Medicine, in Baltimore, who was not involved in the study.

Cancer cells, by their very nature, tend to be genetically unstable. And it is thought that this instability leads to the generation of tumor cell populations, also known as subclones, that possess different mutations and behaviors. Indeed, genetic differences have been shown to affect the growth rate, metastatic potential, and tumorigenicity of individual subclones, as well as their response to therapy.

Of all these behaviors, tumorogenicity—the ability to give rise to new tumors— particularly interestedJohn Dick, a cancer biologist at the University of Toronto. “The only cells that are really important in a tumor, are the cells that are able to propagate that tumor for the long-term,” said Dick. Because, he explained, if any such cells are left behind after treatment, they could recreate a new tumor.

Even among tumorigenic cancer cells, however, behavior is not uniform. A tumorogenicity assay—in which researchers dissociated cells from a human tumor and injected them into mice to form new tumors, then repeated the procedure four more times—revealed considerable variety in the subclones that contributed to the new tumors. Some were detectable in each of the five new tumors, while others dwindled after the first tumor, suggesting they either lost their tumorigenicity, or became dormant. Some subclones were initially undetectable, but became abundant in later tumors, suggesting they had been dormant and then ramped up their proliferation. And others still varied in their contribution from tumor to tumor, appearing to be dormant in some and active in others.

To test if this heterogeneity reflected genetic differences among the subclones, the team performed whole-exome sequencing and other genetic comparisons. To their surprise, the cells were indistinguishable. “The bottom line was that we saw remarkable genetic stability,” said Dick. ”This wide functional behavior of clones . . . was not reflected in their genetics.”

Even more surprising to Dick was the fact that the subclones also differed widely in their responses to a common chemotherapy drug, oxaliplatin—specifically, in their abilities to regrow tumors. Interestingly, cells that had previously robustly turned up in every new tumor dwindled in quantity following treatment with oxaliplatin, while subclones that had not appeared early on began to flourish. “The conclusion that we came to was that there must be non-genetic mechanisms that are governing drug resistance,” said Dick. Not only that, the results also suggested that cell dormancy itself was a mechanism of drug-resistance.

This is important, because it might explain why some cancers recur after treatment, said Dick. “Chemotherapy is mostly targeted to cells that are proliferating,” he explained. Indeed, said Mel Greaves, professor of cell biology at the Institute of Cancer Research in London, “the genetic plus epigenetic or phenotypic diversity of cancer stem cells is probably a major reason for the clinical intransigence of most advanced cancers.”

“There’s a huge enterprise and belief that if we sequence more tumors and identify more mutations . . . that we are going to be able to effect more cancer cures,” said Dick. While he doesn’t doubt the importance of such endeavors, he suggested studying epigenetic and microenvironmental factors affecting cancer cell heterogeneity is also essential. “We should not be putting our eggs exclusively in the genetics basket,” he said.

A. Kreso et al., “Variable clonal repopulation dynamics influence chemotherapy response in colorectal cancer,” Science, doi: 10.1126/science.1227670, 2012.

Wednesday, December 12, 2012

Mike Tyson Grateful

Boxing icon grateful
By GEORGE WILLIS
Last Updated: 5:51 AM, December 9, 2012
Posted: 2:24 AM, December 9, 2012


LAS VEGAS — Mike Tyson was a visible presence leading up to the Manny Pacquiao-Juan Manuel Marquez fight last night at the MGM Grand Garden Arena. He was the official observer for the weigh-in Friday, worked radio row in the media center and attended an autograph signing for Tecate a few hours before the fight.

More important, he launched his new charitable foundation, Mike Tyson Cares, with a reception Friday night at the MGM Grand — the site of the various high and lows during his career.

The easy manner in which Tyson worked the room, drawing crowds wherever he went and mingling with friends and strangers with an embracing personality, was further evidence of a man grateful he did not wind up like Hector “Macho” Camacho.


“I was saying to myself that could have easily been me if I didn’t have these life changes,” Tyson said. “I remember being in a state where I said, ‘I’m not going to pay the drug guy. I’m tired of paying.’ All of a sudden I’m a tough guy. Somebody might be scared to fight and he sees you when you’re not expecting it because your guard is down and that’s what happens.

“Not saying that happened to Hector, but that’s the way I lived my life when I was out there like that before I changed my lifestyle.”

Camacho, a world champion boxer from Puerto Rico and Spanish Harlem, died last month from gun shots wounds suffered during an assault in Puerto Rico. A passenger in the same car as Camacho, who was killed instantly, had nine bags of cocaine in his possession.

It was the kind of ending many feared for Tyson, who had his own battles with drug addiction. But the former heavyweight champion, who was once convicted of rape, has re-invented himself.

He recently announced his one-man show, “Mike Tyson: Undisputed Truth,” will embark on a 10-week national tour beginning in February. “Undisputed Truth” premiered in Las Vegas in April and had a 12-show run on Broadway this summer. The tour begins in Indianapolis on Feb. 12-Feb. 13 and will stop at the Beacon Theatre on April 28.

Tyson’s performances have drawn mostly positive reviews.

“The stage gets me high,” he said. “My fans get me high. That’s that high I was looking for when I was doing drugs and could never receive it. And now it’s back and I’m back doing what I like to do, and that’s entertaining my fans and giving a better perspective of who I am.”

He’s also serious about his foundation. Sugar Ray Leonard, Thomas Hearns, Earnie Shavers, Leon Spinks, and HBO broadcaster Jim Lampley were among the notables at the launch party. The mission of the foundation is to give kids a fighting chance by offering innovative centers that provide for children from broken homes.

“I want to leave a legacy of caring for people,” Tyson said. “That’s what’s on my mind now. I want to champion that more so than being a so-called celebrity guy. I never realized giving would give you so much fulfillment. That’s what I’m about now.”

Camacho’s death at age 50 has given Tyson a clearer vision of what he wants do with his own survival.

“There’s so much satisfaction in helping these people, just the way I needed help,” Tyson said. “I was one of these kids. Whoever believed a guy like that could become a guy like Mike Tyson and have a big reputation with people all over the world.

“I’m just so grateful for Cus D’Amato and Bobby Stewart and all those guys because I didn’t think anything like that could ever happen.”

Tuesday, December 11, 2012

New drug lifts hard-to-treat depression in hours

16:46 11 December 2012 by Jessica Hamzelou
Magazine issue 2895. Subscribe and save
For similar stories, visit the Mental Health Topic Guide

Depression need not linger if a new class of drugs that can improve symptoms within hours becomes available.

People with depression are often treated with drugs that increase levels of serotonin and other mood-enhancing chemicals in the brain. But these drugs typically take weeks, or even months, to work.

Drugs that target receptors for a chemical called NMDA appear to take effect much faster. Ketamine is one example. It can reduce symptoms of depression within hours, but also has hallucinatory side effects.

Now Joseph Moskal and colleagues at Northwestern University in Evanston, Illinois, have trialled a similar drug called GLYX-13, which also targets NMDA receptors. Moskal's team gave either GLXY-13 or a placebo to 116 people with depression that did not respond to other treatments.

Those who received the drug reported that their symptoms got better within two hours, with no significant side effects. The drug also performed significantly better than the placebo. The team presented their results at theAmerican College of Neuropsychopharmacology annual meeting in Hollywood, Florida, last week.

Moskal reckons the drug works by boosting either the strength or number of connections between neurons, although it is not yet clear why this improves symptoms.

Gerard Sanacora at Yale School of Medicine thinks that people with depression may experience a slump in activity in the frontal cortex of the brain, and that the drug might reverse this. "I'm excited about this whole class of drugs," he says. "It opens up a new vista for drug development for these disorders, although there's still a lot of work to be done." Moskal says he is aiming to get the drug to market by 2016.

Crow Snowboarding


Turning urine into brain cells


A new method for generating brain cells from urine samples could be useful for research into neurodegenerative diseases and for screening for new drugs


Neural progenitors derived from human urine cells stained with antibodies against neural stem cell markers Nestin (green) and Pax6 (red). Credit: Lihui Wang, Guangjin Pan and Duanqing Pei.


Chinese researchers have devised a new technique for reprogramming cells from human urine into immature brain cells that can form multiple types of functioning neurons and glial cells. The technique, published today in the journal Nature Methods, could prove useful for studying the cellular mechanisms of neurodegenerative conditions such as Alzheimer's and Parkinson's and for testing the effects of new drugs that are being developed to treat them.

Stem cells offer the hope of treating these debilitating diseases, but obtaining them from human embryos poses an ethical dilemma. We now know that cells taken from the adult human body can be made to revert to a stem cell-like state and then transformed into virtually any other type of cell. This typically involves using genetically engineered viruses that shuttle control genes into the nucleus and inserts them into the chromosomes, whereupon they activate genes that make them pluripotent, or able to re-differentiate into another type of cell.

In 2008, for example, American researchers took skin cells from an 82-year-old patient with amyotrophic lateral sclerosis and reprogrammed them into motor neurons. Cells obtained in this way could help us gain a better understanding of such diseases. Grafts of patients' own cells do not elicit an immune response, so this approach may eventually lead to effective cell transplantation therapies. But it also has its problems – it appears that the reprogramming process destabilizes the genome and causes mutations, and that iPSCs may therefore harbour genetic defectsthat render them useless.

Last year, Duanqing Pei of the Chinese Academy of Sciences and his colleagues reported that human urine contains skin-like cells from the lining of the kidney tubules which can be efficiently reprogrammed, via the pluripotent state, into neurons, glia, liver cells and heart muscle cells. Now they have improved on the approach, making it quicker, more efficient and possibly less prone to errors.

In the new study, they isolated cells from urine samples given by three donors, aged 10, 25 and 37, and converted them directly into neural progenitors. They then grew these cells in Petri dishes and drove them to differentiate into mature neurons that can generate nervous impulses, and also into astrocytes and oligodendrocytes, two types of glial cell found in the human brain. Finally, they transplanted the re-programmed neurons and astrocytes into the brains of newborn rats, and found that the cells had survived when they examined the brains a month later, but it remains to be seen if they can survive for longer, and if they integrate into the existing circuits to be become functional.

This isn't the first time that one type of cell has been converted into another without going through the pluripotent stage – in 2010, researchers from Stanford converted mouse connective tissue cells directly into neurons. The new technique does have a number of advantages, however.

Instead of using a virus to deliver the reprogramming genes, the researchers used a small circular piece of bacterial DNA which can replicate in the cytoplasm. This not only speeds up the process, but also eliminates the need to integrate the reprogramming genes into the chromosome, which is one potential source of genetic mutation, but it's still not clear whether these cells contain fewer mutations than those reprogrammed using viruses.

Even so, the technique also makes the procedure of generating iPSCs far easier and non-invasive, as the cells can be obtained from a urine sample instead of a blood sample or biopsy. The next logical step will be to generate neurons from urine samples obtained from patients with Alzheimer's, Parkinson's, and other neurodegenerative diseases and to determine the extent to which this new non-viral technique damages the DNA.

Reference: Wang, L., et al. (2012). Generation of integration-free neural progenitor cells from cells in human urine. Nature Methods, doi:10.1038/Nmeth.2283

BigPic: A Frost-Covered Mountain Range On Pockmarked Mars

BigPic: A Frost-Covered Mountain Range On Pockmarked Mars
ESA's Mars Express orbiter snaps some 3-D images.
By Rebecca Boyle


Charitum Montes ESA’s Mars Express took this high-resolution view of Charitum Montes, seen here in natural color. Centered around 53°S and 334°E, the image has a ground resolution of about 20 meters per pixel. The heavily cratered region in this image is at the edge of the almost 1,000-kilometer-long mountain range, which itself wraps around the boundary of the Argyre impact basin, the second largest on Mars.Click here to make it bigger. ESA/DLR/FU Berlin (G. Neukum)

The high-resolution image above shows a region on Mars called Charitum Montes, a mountain range on the planet’s southern hemisphere. The brighter features are covered in seasonal carbon dioxide frost.

ESA’s Mars Express orbiter shot these photos in June, which would have been winter in the southern hemisphere. The terrain here is very old, which you can tell by the filled-in craters. The area also has smaller pedestal craters, where the ejected material forms a plateau in the surrounding area. ESA explains: “The ejecta surrounding pedestal craters form erosion-resistant layers, meaning that the immediate vicinity around the crater erodes more slowly than the surrounding terrain. The resistant ejecta layer is largely untouched, forming the pedestal.” These stand out in three dimensions thanks to the Mars Express stereo camera.



Charitum Montes Detail: ESA/DLR/FU Berlin (G. Neukum)



Look at the image above for some further detail. This large crater shows some interesting sedimentary deposits, which appear to have entered the crater through a breach in its northern rim. Several of the other annotated boxes also depict dunes and sedimentary deposits. Planetary geologists are studying these features to determine how they form.

As the Mars rover Curiosity and its predecessors have shown, Mars once had plenty of water flowing across its surface, which is a likely culprit in forming these deposits.



Charitum Montes In Context: Charitum Montes is a mountain range bounding the southern rim of Mars' Argyre impact basin. It's near Galle Crater, not to be confused with Gale Crater. Galle Crater is notable for its prominent smiley face. ESA

FYI: Why Are Mean People So Hot?

It's not that meanies are more physically attractive than everyone else. They're just very good at fooling us.
By Julie Beck


Mean Girls MOVIECLIPS on YouTube

Mean people are attractive because of their meanness, not in spite of it. What I call meanness is more officially known as the “Dark Triad” of personality traits—narcissism, Machiavellianism and psychopathy. A recent study shows that people who exhibit these traits are better than people who score lower on the Dark Triad at making themselves appear more attractive.

The meanies aren't necessarily more physically attractive than anyone else, they are just better at using what the study calls “adornments” (clothes, makeup and the like) to make themselves seem more appealing. The researchers, Nicholas Holtzman and Michael Strube at Washington University in St. Louis, had their subjects remove all makeup, pull long hair back into a ponytail and don a white T-shirt and grey sweatpants. They were rated on their attractiveness in this unadorned state, set loose to adorn themselves to their hearts' content, and rated again. All three Dark Triad traits were associated with higher attractiveness in the adorned state, when controlling for attractiveness in the unadorned state. So you can take some small comfort in knowing that mean people are just as ugly as the rest of us, they're just better at fooling everyone into thinking they're hot.

Mean people are just as ugly as the rest of us, they're just better at fooling everyone into thinking they're hot.

The study suggests a possible reason why these subjects were compelled to make themselves more attractive: “When people high in Dark Triad traits dress-up, they may experience greater increments in self-esteem or derive more satisfaction from the additional attention they receive, compelling them to continue dressing well.”

And it has been well-documented that the physically attractive are seen as more likeable, further explaining the popularity of the bad boys in their motorcycle jackets who make the ladies swoon, and the cruel, selfish high school girls with expensive hair and logo-emblazoned t-shirts. As “Mean Girls”—yet another incisive cultural study—put it: “The weird thing about hanging out with Regina was that I could hate her, and at the same time, I still wanted her to like me.”

The inexplicable pull of Regina George, the cruel, popular ringleader, goes beyond just her physical beauty, artificial or not. Her Dark Triad personality traits may actually be helping her. Psychopaths have long been characterized as outwardly charming, and research suggests that narcissists tend to make better first impressions. Studies show that after brief exposure to a new person, people rated those who ranked high for narcissism as more likeable.

But whether your personal Regina George gets hit by a bus or not, beauty will fade with time, and even the strongest first impression can't hide a truly dark interior forever. So chin up, because someday you'll be living in a big old city, and all they're ever gonna be is mean.

Hacking the Human Brain: The Next Domain of Warfare

BY CHLOE DIGGINS AND CLINT ARIZMENDI
12.11.12 9:30 AM



Photo: Joint Base Lewis McChord / Flickr

It’s been fashionable in military circles to talk about cyberspace as a “fifth domain” for warfare, along with land, space, air and sea. But there’s a sixth and arguably more important warfighting domain emerging: the human brain.

This new battlespace is not just about influencing hearts and minds with people seeking information. It’s about involuntarily penetrating, shaping, and coercing the mind in the ultimate realization of Clausewitz’s definition of war: compelling an adversary to submit to one’s will. And the most powerful tool in this war is brain-computer interface (BCI) technologies, which connect the human brain to devices.

Chloe Diggins and Clint Arizmendi are research & analysis officers at the Australian army’s Land Warfare Studies Centre. The views expressed are their own and do not reflect those of the Australian Department of Defence or the Australian Government.



Current BCI work ranges from researchers compiling and interfacing neural data such as in the Human Conectome Project to work by scientists hardening the human brain against rubber hose cryptanalysis to technologists connecting the brain to robotic systems. While these groups are streamlining the BCI for either security or humanitarian purposes, the reality is that misapplication of such research and technology has significant implications for the future of warfare.

Where BCIs can provide opportunities for injured or disabled soldiers to remain on active duty post-injury, enable paralyzed individuals to use their brain to type, or allow amputees to feel usingbionic limbs, they can also be exploited if hacked. BCIs can be used to manipulate … or kill.

Recently, security expert Barnaby Jack demonstrated the vulnerability of biotechnological systems by highlighting how easilypacemakers and implantable cardioverter-defibrillators (ICDs) could be hacked, raising fears about the susceptibility of even life-saving biotechnological implants. This vulnerability could easily be extended to biotechnologies that connect directly to the brain, such as vagus nerve stimulation or deep-brain stimulation.

Outside the body, recent experiments have proven that the brain can control and maneuverquadcopter drones and metal exoskeletons. How long before we harness the power of mind-controlled weaponized drones – or use BCIs to enhance the power, efficiency, and sheer lethality of our soldiers?
This new battlespace is not just about influencing hearts and minds. It’s about involuntarily penetrating and coercing the mind.

Given that military research arms such as the United States’ DARPA are investing in understanding complex neural processesand enhanced threat detection through BCI scan for P300responses, it seems the marriage between neuroscience and military systems will fundamentally alter the future of conflict.

And it is here that military researchers need to harden the systems that enable military application of BCIs. We need to prevent BCIs from being disrupted or manipulated, and safeguard against the ability of the enemy to hack an individual’s brain.

The possibilities for damage, destruction, and chaos are very real. This could include manipulating a soldier’s BCI during conflict so that s/he were forced to pull the gun trigger on friendlies, install malicious code in his own secure computer system, call in inaccurate coordinates for an air strike, or divulge state secrets to the enemy seemingly voluntarily. Whether an insider has fallen victim to BCI hacking and exploits a system from within, or an external threat is compelled to initiate a physical attack on hard and soft targets, the results would present major complications: in attribution, effectiveness of kinetic operations, and stability of geopolitical relations.

Like every other domain of warfare, the mind as the sixth domain is neither isolated nor removed from other domains; coordinated attacks across all domains will continue to be the norm. It’s just that military and defense thinkers now need to account for the subtleties of the human mind … and our increasing reliance upon the brain-computer interface.

Regardless of how it will look, though, the threat is real and not as far away as we would like – especially now that researchers just discovered a zero-day vulnerability in the brain.

Porcupines Inspire Less-Painful NeedlesBy Tech News Daily Staff | LiveScience.com

Porcupine quills could inspire a new class of less-painful medical needles that slide effortlessly through flesh, scientists say.

In a new study, researchers examined porcupine quills to characterize the forces they need to enter and exit the skin. The researchers used as their model the North American porcupine, which has about 30,000 barbed quills to defend against predators. Each quill is several centimeters long, with tips covered in microscopic, backward-facing barbs.

These barbs allow the quills to slide easily into flesh, but make them difficult to pull out. The barbs act to localize the penetration forces, allowing the quills to tear through tissue fibers much more easily, just as a serrated knife cuts through tomato skin far more cleanly than a straight-edged knife.

When it comes to the force required for the pullout, the barbs act like anchors that keep the quill from exiting.

[New Patch Poised to Replace Needles For Painless Flu Shot ]

To determine the full importance of the barbs, the researchers carefully removed them from some quills and compared these smoother quills to regular, barbed quills. Tests found that barbed quills require 60 to 70 percent less force to penetrate muscle tissue and were four times harder to remove.

Using what they've learned, the researchers have already created a synthetic porcupine quill that they will test in a variety of medical applications. They think the synthetic quills could be tweaked so they can penetrate tissue easily, without being as difficult to remove as real porcupine quills.

"If you can still create the stress concentrations, but without having a barb that catches tissue on removal, potentially you could create something with just easy insertion, without the adhesion," study coauthor James Ankrum of MIT said in a statement.

The synthetic quills could function not only as less-painful needles for injection, but as alternatives to staples used in surgery.

Porcupine quills "can strongly grip tissue with minimal depth of penetration, less than half a centimeter is enough and they don't need to bend like staples to achieve secure fixation," Ankrum said.

The grippy barbs on porcupine quills could also lead to stronger adhesives that can bind internal tissues more securely, the team says.

There is a great need for such adhesives, especially in patients who have undergone gastric-bypasssurgery or other types of gastric or intestinal surgery, according to the researchers. These surgical incisions are now sealed with sutures or staples, which can leak and cause complications.

The research is detailed in this week's issue of the journal the Proceedings of the National Academy of Sciences.

This story was provided by TechNewsDaily.com, a sister site to LiveScience.com.

Thursday, December 6, 2012

Austerity and War: Destroying Human Rights By John Perkins

December 5, 2012
Austerity and War: Destroying Human Rights
By John Perkins

Holiday crowds swarmed the streets of downtown Seattle. Christmas lights and music filled the night with a festive spirit. My daughter Jessica, five-year old grandson Grant, and our friend Mark left the hustle and bustle of elegant shops and made our way down Marion St., headed for the ferry terminal. As we crossed the pedestrian bridge that arches above the Alaskan Way, we came upon the cluster of homeless people who hang out in the shadows of the ferry terminal. Among the familiar signs perched near them, I spotted a new one: “Iraq Vet. – Austerity and war destroy human rights.”

It was so reminiscent of an article I had recently read by my friend Laura Flanders entitled “Austerity: A Violation of Human Rights?” that I figured the bearded veteran hunkered down behind the sign must have seen that same article. (http://www.thenation.com/blog/171364/austerity-violation-human-rights)

The issues around government, economics, and war raise serious questions. All of us, especially we who are citizens of the United States and the European and Asian countries that today control the global economy – one that is obviously failing – must ask ourselves: What impact do the austerity policies proposed by politicians have on human rights? How about war?

Flander’s article points out that President Franklin D. Roosevelt in 1941 defined the “Four Freedoms” essential to good democracy and human rights as: the freedom of speech and expression, freedom of worship, freedom from want, and freedom from fear. These concepts were incorporated into the U.N.’s Universal Declaration of Human Rights in 1948.

Riding the ferry across Puget Sound and watching Grant snuggle into his mother’s lap as she read a Christmas story to him, I kept thinking about that Iraqi Veteran. It seemed to me that his government, the one he fought for, has taken the last two of FDR’s freedoms away from him.

“Freedom from want” was the keystone of FDR’s New Deal and has been considered a necessary element to good governance ever since. Yet in 2010, 46.9 million people in the U.S. were classified as living in poverty– the fourth consecutive annual increase and the largest number in the 52 years for which poverty rates have been published (the 2011 and 2012 numbers will probably be even higher, although not yet published). Globally, about 1 billion people are officially classified as hungry; however, governments tend to underestimate these figures: in reality roughly half the world is malnourished, approaching starvation, or actually starving.

“Freedom of fear” has new implications in a country so obsessed with fighting terrorism that its officials pass laws which strike fear into anyone in a position to seriously criticize government policies and the authorities who enforce them. These laws include warrantless searches, secret intelligence (and military) courts, extraordinary renditions, and the denial of habeas corpus, a guarantee that no one shall be detained without sufficient evidence and that anyone arrested will have a speedy trial. Regardless of your opinions about Guantanamo, police brutality against the Occupy Movement and unions, and Bradley Manning, you have to wonder . . .

Those who would keep us in a state of war mentality understand that the threat of war is their avenue to increased riches (since they are the military-industrial complex) and the simplest way to perpetuate fear and the draconian laws that walk hand in hand with it. The war economy also assures huge budget deficits – which in turn offer an excuse for cutting back on social services for the poor and middle classes. The U.S. military budget is more than 50% of the world total; yet among the 34 OEDC countries the U.S. ranks last in spending on social services. Alexis de Tocqueville, the 19th century historian and author of Democracy in America, wrote: “All those who seek to destroy the liberties of a democratic nation ought to know that war is the surest and shortest means to accomplish it.”

As the debates rage in Washington and throughout Europe over trade-offs between raising taxes on the rich and cutting social services for everyone else, as we muddle through the militaristic flag-waving that brings us closer to war in the Middle East and create a mushroom cloud of national debt, and as we continue to grant oil and other mega-companies huge concessions to ravage lands and cultures around the planet, we might be well advised to heed the message of a man who went to Iraq and now sits in the cold shadows of the Seattle ferry terminal: “Austerity and war destroy human rights.”

Tuesday, December 4, 2012

Cults & Mind Control (What is a Cult?)



What is a cult?  Cults & Mind Control by Michael D.Langone, Ph.D.

A cult is a group or movement exhibiting a great or excessive devotion or dedication to some person, idea, or thing, and employing unethically manipulative techniques of persuasion and control designed to advance the goals of the group’s leader, to the actual or possible detriment of members, their families, or the community.

These groups tend to dictate, sometimes in great detail, how members should think, act, and feel, claim a special exalted status for themselves and/or their leader(s), and intensify their opposition to and alienation from society at large.

Because the capacity to exploit human beings is universal, any group could become a cult. However, most mainstream, established groups have accountability mechanisms that restrain the development of cultic subgroups.

How Many Cults Exist and How Many Members Do They Have?

Cult-education organizations have received inquiries about more than 3,000 groups. Although the majority of groups are small, some have tens of thousands of members. Experts estimate that five to ten million people have been involved with cultic groups at one time or another.

What is Mind Control?

Mind control (also known as “brainwashing,” “coercive persuasion,” and “thought reform”) refers to a process in which a group or individual systematically uses unethically manipulative methods to persuade others to conform to the wishes of the manipulator(s).

Such methods include the following:
  • Extensive control of information in order to limit alternatives from which members may make “choices”
  • Deception
  • Group Pressure
  • Intense indoctrination into a belief system that denigrates independent critical thinkingand considers the world outside the group to be threatening, evil, or gravely in error an insistence that members’ distress-much of which may consist of anxiety and guilt subtly induced by the group-can be relieved only by conforming to the group
  • Physical and/or psychological debilitation through inadequate diet or fatigue the induction of dissociative (trance-like) states via the misuse of meditation, chanting,speaking in tongues, and other exercises in which attention is narrowed, suggestibility heightened, and independent critical thinking weakened
  • Alternation of harshness/threats and leniency/love in order to effect compliance with the leadership’s wishes isolation from social supports pressured public confessions
Who Joins Cults and Why?

Contrary to a popular misconception that cult members are “crazy,” research and clinical evidence strongly suggests that most cult members are relatively normal.

They include the young, the middle-aged, elderly, the wealthy, the poor, the educated, and the uneducated from every ethnic and religious background. There is no easily identifiable type of person who joins cults.

How Do People Who Join Cults Change?
After converts commit themselves to a group, the cult’s way of thinking, feeling, and acting becomes second nature, while important aspects of their pre-cult personalities are suppressed or, in a sense, decay through disuse.

New converts at first frequently appear to be shell-shocked; they may appear “spaced out,” rigid and stereotyped in their responses, limited in their use of language, impaired in their ability to think critically, and oddly distant in their relationships with others. Intense cultic manipulations can trigger altered states of consciousness in some people.

Why Do People Leave Cults?

People leave for a variety of reasons. After becoming aware of hypocrisy and/or corruption within the cult, converts who have maintained an element of independence and some connection with their old values may simply walk out. Others may leave because they are weary of a routine of proselytizing and fund-raising.

Sometimes even the most dedicated members may feel so inadequate in the face of the cult’s demands that they walk away because they feel like abject failures. Others may renounce the cult after reconnecting to old values, goals, interests, or relationships, resulting from visits with parents, talks with ex-members, or exit counseling.

Is Leaving a Cult Easy?

People who consider leaving a cult are usually pressured to stay. Some ex-members say they spent months, even years, trying to garner the strength to walk out. Some felt so intimidated they departed secretly.

Although many cult members eventually walk out on their own, many, if not most, who leave cults on their own are psychologically harmed, often in ways they do not understand. Some cult members never leave, and some of these are severely harmed.

There is no way to predict who will leave, who won’t leave, or who will be harmed. ?

Cults Formation by Robert Jay Lifton, M.D.

Two main concerns should inform our moral and psychological perspective on cults:
  1. the dangers of ideological totalism, or what I would also call fundamentalism
  2. the need to protect civil liberties
There is now a worldwide epidemic of totalism and fundamentalism in forms that are political, religious or both. Fundamentalism is a particular danger in this age of nuclear weapons, because it often includes a theology of Armageddon–a final battle between good and evil.

I have studied Chinese thought reform in the 1950s as well as related practices in McCarthyite American politics and in certain training and educational programs. I have also examined these issues in work with Vietnam veterans, who often movingly rejected war related totalism; and more recently in a study of the psychology of Nazi doctors.

Certain psychological themes which recur in these various historical contexts also arise in the study of cults.

Cults can be identified by three characteristics:
  • A charismatic leader who increasingly becomes an object of worship as the general principles that may have originally sustained the group lose their power
  • A process I call coercive persuasion or thought reform
  • Economic, sexual, and other exploitation of group members by the leader and the ruling coterie
Milieu Control

The first method characteristically used by ideological totalism is milieu control: the control of all communication within a given environment. In such an environment individual autonomy becomes a threat to the group. There is an attempt to manage an individual’s inner communication.

Milieu control is maintained and expressed by intense group process, continuous psychological pressure, and isolation by geographical distance, unavailability of transportation, or even physical restraint. Often the group creates an increasingly intense sequence of events such as seminars, lectures and encounters which makes leaving extremely difficult, both physically and psychologically.

Intense milieu control can contribute to a dramatic change of identity which I call doubling: the formation of a second self which lives side by side with the former one, often for a considerable time.

When the milieu control is lifted, elements of the earlier self may be reasserted.
Creating a Pawn

A second characteristic of totalistic environments is mystical manipulation or planned spontaneity. This is a systematic process through which the leadership can create in cult members what I call the psychology of the pawn. The process is managed so that it appears to arise spontaneously; to its objects it rarely feels like manipulation.

Religious techniques such as fasting, chanting and limited sleep are used. Manipulation may take on a special intense quality in a cult for which a particular chosen’ human being is the only source of salvation. The person of the leader may attract members to the cult, but can also be a source of disillusionment. If members of the Unification Church, for example, come to believe that Sun Myung Moon, its founder, is associated with the Korean Central Intelligence Agency, they may lose their faith.

Mystical manipulation may also legitimate deception of outsiders, as in the “heavenly deception” of the Unification Church and analogous practices in other cult environments. Anyone who has not seen the light and therefore lives in the realm of evil can be justifiably deceived for a higher purpose.

For instance, collectors of funds may be advised to deny their affiliation with a cult that has a dubious public reputation.

Purity and Confession

Two other features of totalism are a demand for purity and a cult of confession. The demand for purity is a call for radical separation of good and evil within the environment and within oneself. Purification is a continuing process, often institutionalized in the cult of confession, which enforces conformity through guilt and shame evoked by mutual criticism and self-criticism in small groups.

Confessions contain varying mixtures of revelation and concealment.

As Albert Camus observed, “Authors of confessions write especially to avoid confession, to tell nothing of what they know.”

Young cult members confessing the sins of their precultic lives may leave out ideas and feelings that they are not aware of or reluctant to discuss, including a continuing identification with their prior existence.

Repetitious confession, especially in required meetings, often expresses an arrogance in the name of humility. As Camus wrote:
“I practice the profession of penitence to be able to end up as a judge,” and, “The more I accuse myself, the more I have a right to judge you.”

Three further aspects of ideological totalism are “sacred science,” “loading of the language,” and the principle of “doctrine over person.” Sacred science is important because a claim of being scientific is often needed to gain plausibility and influence in the modern age.

The Unification Church is one example of a contemporary tendency to combine dogmatic religious principles with a claim to special scientific knowledge of human behavior and psychology. The term ‘loading the language’ refers to literalism and a tendency to deify words or images. A simplified, cliché-ridden language can exert enormous psychological force reducing every issue in a complicated life to a single set of slogans that are said to embody the truth as a totality.

The principle of doctrine over person’ is invoked when cult members sense a conflict between what they are experiencing and what dogma says they should experience. The internalized message of the totalistic environment is that one must negate that personal experience on behalf of the truth of the dogma. Contradictions become associated with guilt: doubt indicates one’s own deficiency or evil.

Perhaps the most significant characteristic of totalistic movements is what I call “dispensing of existence.” Those who have not seen the light and embraced the truth are wedded to evil, tainted, and therefore in some sense, usually metaphorical, lack the right to exist.

That is one reason why a cult member threatened with being cast into outer darkness may experience a fear of extinction or collapse. Under particularly malignant conditions, the dispensing of existence is taken literally; in the Soviet Union, Nazi Germany, and elsewhere, people were put to death for alleged doctrinal shortcomings. In thePeople’s Temple mass suicide-murder in Guyana, a cult leader presided over the literal dispensing of existence by means of a suicidal mystique he himself had made a central theme in the group’s ideology.

The totalistic impulse to draw a sharp line between those who have the right to live and those who do not is especially dangerous in the nuclear age.

Historical Context

Totalism should always be considered within a specific historical context. A significant feature of contemporary life is the historical (or psycho historical) dislocation resulting from a loss of the symbolic structures that organize ritual transitions in the life cycle, and a decay of belief systems concerning religion, authority, marriage, family, and death.

One function of cults is to provide a group initiation rite for the transition to early adult life, and the formation of an adult identity outside the family. Cult members have good reasons for seeing attempts by the larger culture to make such provisions as hypocritical or confused.

In providing substitute symbols for young people, cults are both radical and reactionary. They are radical because they suggest rude questions about middle-class family life and American political and religious values in general. They are reactionary because they revive pre-modern structures of authority and sometimes establish fascist patterns of internal organization.

Furthermore, in their assault on autonomy and self-definition some cults reject a liberating historical process that has evolved with great struggle and pain in the West since the Renaissance. Cults must be considered individually in making such judgments. Historical dislocation is one source of what I call the “protean style.”

This involves a continuous psychological experimentation with the self, a capacity for endorsing contradictory ideas at the same time, and a tendency to change one’s ideas, companions and way of life with relative ease. Cults embody a contrary ‘restricted style,’ a flight from experimentation and the confusion of a protean world. These contraries are related: groups and individuals can embrace a protean and a restricted style in turn.

For instance, the so-called hippie ethos of the 1960s and 1970s has been replaced by the present so-called Yuppie preoccupation with safe jobs and comfortable incomes. For some people, experimentation with a cult is part of the protean search.

The imagery of extinction derived from the con temporary threat of nuclear war influences patterns of totalism andfundamentalism throughout the world. Nuclear war threatens human continuity itself and impairs the symbols of immortality. Cults seize upon this threat to provide immortalizing principles of their own.

The cult environment supplies a continuous opportunity for the experience of transcendence — a mode of symbolic immortality generally suppressed in advanced industrial society.

Role of Psychology

Cults raise serious psychological concerns, and there is a place for psychologists and psychiatrists in understanding and treating cult members.

But our powers as mental health professionals are limited, so we should exercise restraint. When helping a young person confused about a cult situation, it is important to maintain a personal therapeutic contract so that one is not working for the cult or for the parents.

Totalism begets totalism. What is called deprogrammingincludes a continuum from intense dialogue on the one hand to physical coercion and kidnapping, with thought-reform-like techniques, on the other. My own position, which I have repeatedly conveyed to parents and others who consult me, is to oppose coercion at either end of the cult process. Cults are primarily a social and cultural rather than a psychiatric or legal problem.

But psychological professionals can make important contributions to the public education crucial for dealing with the problem. With greater knowledge about them, people are less susceptible to deception, and for that reason some cults have been finding it more difficult to recruit members.

Yet painful moral dilemmas remain. When laws are violated through fraud or specific harm to recruits, legal intervention is clearly indicated. But what about situations in which behavior is virtually automatized, language reduced to rote and cliché, yet the cult member expresses a certain satisfaction or even happiness?

We must continue to seek ways to encourage a social commitment to individual autonomy and avoid coercion and violence.

The NDAA Legalizes The Use Of Propaganda On The US Public

The newest version of the National Defense Authorization Act (NDAA) includes an amendment that would legalize the use of propaganda on the American public, reports Michael Hastings of BuzzFeed.

The amendment — proposed by Mac Thornberry (R-Texas) and Adam Smith (D-Wash.) and passed in the House last Friday afternoon — would effectively nullify the Smith-Mundt Act of 1948, which explicitly forbids information and psychological operations aimed at influencing U.S. public opinion.

Thornberry said that the current law “ties the hands of America’s diplomatic officials, military, and others by inhibiting our ability to effectively communicate in a credible way,” according to Buzzfeed.

The vote came two days after a federal judged ruled that an indefinite detention provision in the annual defense bill was unconstitutional.

Lt. Col. Daniel Davis, who released a highly critical report regarding the distortion of truth by senior military officials in Iraq and Afghanistan, dedicated a section of his report to Information Operations (IO) and states that after Desert Storm the military wanted to transform IO "into a core military competency on a par with air, ground, maritime and special operations."

santa
(1942 Propoganda Santa)

Davis defines IO as "the integrated employment of electronic warfare (EW), computer network operations (CNO), psychological operations (PSYOP), military deception (MILDEC), and operations security (OPSEC), in concert with specified supporting and related capabilities, to influence, disrupt, corrupt or usurp adversarial human and automated decision making while protecting our own."

IO are primarily used to target foreign audiences, but Davis cites numerous senior leaders who want to "protect a key friendly center of gravity, to wit US national will" by repealing the Smith-Mundt Act to allow the direct deployment of these tactics on the American public.

Davis quotes Brigadier General Ralph O. Baker — the Pentagon officer responsible for the Department of Defense’s Joint Force Development (i.e. Army, Navy, Air Force, and Marines) — who defines IO as activities undertaken to "shape the essential narrative of a conflict or situation and thus affect the attitudes and behaviors of the targeted audience" and equates descriptions of combat operations with standard marketing strategies:

For years, commercial advertisers have based their advertisement strategies on the premise that there is a positive correlation between the number of times a consumer is exposed to product advertisement and that consumer’s inclination to sample the new product. The very same principle applies to how we influence our target audiences when we conduct COIN.

Davis subsequently explains the "cumulative failure of our nation’s major media in every category" as they continually interviewed only those senior U.S. officials who had top-level access, even as the officials given that clearance were required to stick to "talking points" given to them by Secretary of Defense Donald Rumsfeld.

If the NDAA goes into effect in its current form, the State Department and Pentagon can go beyond manipulating mainstream media outlets and directly disseminate campaigns of misinformation to the U.S. public.

Read more: http://www.businessinsider.com/ndaa-legalizes-propaganda-2012-5#ixzz2E7KspJNA

Monday, December 3, 2012

Tibetan protesters setting themselves on fire

Tibetan protesters setting themselves on fire in greater numbers
Published on Wednesday November 28, 2012


FREETIBET.ORG/APDorje Rinchen, a farmer in his late 50s, runs after setting himself on fire last month in a city in China's Gansu province. A surge in self-immolations and large demonstrations by Tibetans marks a new phase in protests against authoritarian Chinese rule in Tibetan areas.  (Christopher Bodeen
Associated Press)

BEIJING—Two dozen Tibetans have set themselves on fire in western China this month in a dramatic acceleration of the protests against authoritarian Chinese rule, activist groups say.

The surge in self-immolations, along with an increase in large demonstrations, marks a new phase in the Tibetan protests.

At least 86 people have set themselves on fire since the immolations began in 2009. In a change in recent months, most self-immolators now are lay people rather than Buddhist monks and nuns, who can be more closely watched by the authorities.

The protests have also sought to avoid direct attacks on authorities and government property, acts which in the past the authorities could label as riots or terrorism, providing an excuse for greater oppression. Despite the altered approach, observers see little short-term possibility of Beijing changing its policies on Tibet.

“The problem will just escalate over time. The government shows no inclination to respond positively to recommendations for reform,” said University of Hong Kong law professor Michael Davis, an expert on Tibet.

In the latest immolation, 24-year-old Kalsang Kyab doused himself with kerosene and set himself alight Tuesday in front of local government offices in Kyangtsa in Aba prefecture, a hotbed of unrest, according to London-based Free Tibet and other groups.

An official in Aba said Wednesday he was aware of the immolations but refused to give any details.

On Monday, about 1,000 students at the Tsolho Medical Institute staged a bold protest about 900 kilometres to the north in Qinghai province. Riot police fired shots into the air and released tear gas and beat the students with rifle butts, sending 20 students to the hospital, some with serious injuries, Free Tibet reported.

Tibetan and surrounding ethnically Tibetan regions have been closed off to most outsiders, and firsthand information from the area is extremely difficult to obtain.

Driving the students to protest was a booklet distributed by authorities that derided the Tibetan language as irrelevant, attacked the exiled Dalai Lama and condemned immolation protests as “acts of stupidity.”

The booklet is the latest in a series of perceived slights and intrusive measures by Chinese authorities that have left Tibetans feeling that the culture, language and Buddhist religion at the core of their identity are under threat.

The combination of immolations and large-scale protests is posing a new challenge for security forces, which have been stationed in large numbers in Tibetan areas in recent years.

Though protests have flared periodically over the decades, tensions boiled over in 2008, when deadly rioting broke out in the capital, Lhasa, and sparked an uprising across large swaths of ethnically Tibetan areas. Since then, security — already tight — has been smothering.

Many Tibetans see the immolations as selfless acts of sacrifice, making it hard for authorities to denounce the immolators. Similarly, protests by students are hard to demonize since they are typically non-violent and centred on issues such as language rights, which are guaranteed under the Chinese constitution.

While local authorities have cracked down hard, authorities in Beijing have said relatively little other than to issue routine denunciations of the Dalai Lama and his followers.

That indicates they are uncertain how to respond in a way that would bolster their authority and prevent the acts of defiance snowballing into a full-blown protest movement, said Robbie Barnett, a Tibet expert at New York’s Columbia University.

“This suggests that the Tibetans have found a way of at least getting under the skin of the authorities,” he said.